Letter by hayashi et Al regarding article, "early repolarization is an independent predictor of occurrences of ventricular fibrillation in the very early phase of acute myocardial infarctions".

Response to Letter Regarding Article, “Early Repolarization Is an Independent Predictor of Occurrences of Ventricular Fibrillation in the Very Early Phase of Acute Myocardial Infarctions” We thank Drs Hayashi and Horie for their comments with regard to our recently published article. Previous reports demonstrated that cardiovascular drugs and heart rate can potentially alter the presence early repolarization. The prescribed medications and heart rate between the patients with and without early repolarization are shown in Table. There was no significant difference in the prescribed medications and heart rate between the 2 groups. When the occurrence of ventricular fibrillation was analyzed, the prescribed medications and heart rate did not differ between the patients with and without a ventricular fibrillation occurrence (Table). Although our study revealed that the prescribed medications and heart rate were not associated with the presence of early repolarization and the occurrence of ventricular fibrillation, further larger studies will be needed to confirm these findings.